In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 10 ( 2021-10-12), p. e0258406-
Abstract:
Hypertension is a major global public health problem. Elevated blood pressure can cause cardiovascular and kidney diseases. We assessed the effectiveness of health education sessions and home support programs in reducing blood pressure among patients with uncontrolled hypertension in a suburban community of Nepal. Methods We conducted a community-based, open-level, parallel-group, cluster randomized controlled trial in Birendranagar municipality of Surkhet, Nepal. We randomly assigned four clusters (wards) into intervention and control arms. We provided four health education sessions, frequent home and usual care for intervention groups over six months. The participants of the control arm received only usual care from health facilities. The primary outcome of this study was the proportion of controlled systolic blood pressure (SBP). The analysis included all participants who completed follow-up at six months. Results 125 participants were assigned to either the intervention (n = 63) or the control (n = 62) group. Of them, 60 participants in each group completed six months follow-up. The proportion of controlled SBP was significantly higher among the intervention participants compared to the control (58.3% vs. 40%). Odds ratio of this was 2.1 with 95% CI: 1.01–4.35 (p = 0.046) and that of controlled diastolic blood pressure (DBP) was 1.31 (0.63–2.72) (p = 0.600). The mean change (follow-up minus baseline) in SBP was significantly higher in the intervention than in the usual care (-18.7 mmHg vs. -11.2 mmHg, p = 0.041). Such mean change of DBP was also higher in the intervention (-10.95 mmHg vs. -5.53 mmHg, p = 0.065). The knowledge score on hypertension improved by 2.38 (SD 2.4) in the intervention arm, which was significantly different from that of the control group, 0.13 (1.8) (p 〈 0.001). Conclusions Multiple health education sessions complemented by frequent household visits by health volunteers can effectively improve knowledge on hypertension and reduce blood pressure among uncontrolled hypertensive patients at the community level in Nepal. Trial registration ClinicalTrial.gov: NCT02981251
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0258406
DOI:
10.1371/journal.pone.0258406.g001
DOI:
10.1371/journal.pone.0258406.g002
DOI:
10.1371/journal.pone.0258406.t001
DOI:
10.1371/journal.pone.0258406.t002
DOI:
10.1371/journal.pone.0258406.t003
DOI:
10.1371/journal.pone.0258406.t004
DOI:
10.1371/journal.pone.0258406.t005
DOI:
10.1371/journal.pone.0258406.s001
DOI:
10.1371/journal.pone.0258406.s002
DOI:
10.1371/journal.pone.0258406.s003
DOI:
10.1371/journal.pone.0258406.s004
DOI:
10.1371/journal.pone.0258406.s005
DOI:
10.1371/journal.pone.0258406.s006
DOI:
10.1371/journal.pone.0258406.s007
DOI:
10.1371/journal.pone.0258406.r001
DOI:
10.1371/journal.pone.0258406.r002
DOI:
10.1371/journal.pone.0258406.r003
DOI:
10.1371/journal.pone.0258406.r004
DOI:
10.1371/journal.pone.0258406.r005
DOI:
10.1371/journal.pone.0258406.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
