In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 1 ( 2023-1-27), p. e0274248-
Abstract:
Hospital-acquired infections (HAIs) are significant problems as public health issues which need attention. Such infections are significant problems for society and healthcare organizations. This study aimed to carry out a systematic review and a meta-analysis to analyze the prevalence of HAIs globally. Methods We conducted a comprehensive search of electronic databases including EMBASE, Scopus, PubMed and Web of Science between 2000 and June 2021. We found 7031 articles. After removing the duplicates, 5430 studies were screened based on the titles/ abstracts. Then, we systematically evaluated the full texts of the 1909 remaining studies and selected 400 records with 29,159,630 participants for meta-analysis. Random-effects model was used for the analysis, and heterogeneity analysis and publication bias test were conducted. Results The rate of universal HAIs was 0.14 percent. The rate of HAIs is increasing by 0.06 percent annually. The highest rate of HAIs was in the AFR, while the lowest prevalence were in AMR and WPR. Besides, AFR prevalence in central Africa is higher than in other parts of the world by 0.27 (95% CI, 0.22–0.34). Besides, E. coli infected patients more than other micro-organisms such as Coagulase-negative staphylococci, Staphylococcus spp. and Pseudomonas aeruginosa. In hospital wards, Transplant, and Neonatal wards and ICU had the highest rates. The prevalence of HAIs was higher in men than in women. Conclusion We identified several essential details about the rate of HAIs in various parts of the world. The HAIs rate and the most common micro-organism were different in various contexts. However, several essential gaps were also identified. The study findings can help hospital managers and health policy makers identify the reason for HAIs and apply effective control programs to implement different plans to reduce the HAIs rate and the financial costs of such infections and save resources.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0274248
DOI:
10.1371/journal.pone.0274248.g001
DOI:
10.1371/journal.pone.0274248.g002
DOI:
10.1371/journal.pone.0274248.g003
DOI:
10.1371/journal.pone.0274248.g004
DOI:
10.1371/journal.pone.0274248.g005
DOI:
10.1371/journal.pone.0274248.t001
DOI:
10.1371/journal.pone.0274248.t002
DOI:
10.1371/journal.pone.0274248.t003
DOI:
10.1371/journal.pone.0274248.t004
DOI:
10.1371/journal.pone.0274248.t005
DOI:
10.1371/journal.pone.0274248.t006
DOI:
10.1371/journal.pone.0274248.s001
DOI:
10.1371/journal.pone.0274248.s002
DOI:
10.1371/journal.pone.0274248.s003
DOI:
10.1371/journal.pone.0274248.s004
DOI:
10.1371/journal.pone.0274248.s005
DOI:
10.1371/journal.pone.0274248.s006
DOI:
10.1371/journal.pone.0274248.r001
DOI:
10.1371/journal.pone.0274248.r002
DOI:
10.1371/journal.pone.0274248.r003
DOI:
10.1371/journal.pone.0274248.r004
DOI:
10.1371/journal.pone.0274248.r005
DOI:
10.1371/journal.pone.0274248.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3