In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 10 ( 2022-10-14), p. e0275584-
Kurzfassung:
Individuals with Parkinson’s disease (PD) present respiratory dysfunctions, mainly due to decreased chest wall expansion, which worsens with the course of the disease. These findings contribute to the restrictive respiratory pattern and the reduction in chest wall volume. According to literature, inspiratory muscle thixotropic conditioning maneuvers may improve lung volumes in these patients. The study aimed to determine the after-effects of respiratory muscle thixotropic maneuvers on breathing patterns and chest wall volumes of PD. A crossover study was performed with twelve patients with PD (8 males; mean age 63.9±8.8 years, FVC %pred 89.7±13.9, FEV 1%pred 91.2±15, FEV 1 /FVC %pred 83.7±5.7). Chest wall volumes were assessed using OEP during thixotropic maneuvers. Increases in EIV CW (mean of 126mL, p = 0.01) and EEV CW (mean of 150mL, p = 0.005) were observed after DI TLC (deep inspiration from total lung capacity) due to increases in pulmonary (RCp) and abdominal (RCa) ribcage compartments. Changes in ICo TLC (inspiratory contraction from TLC) led to significant EIV CW (mean of 224mL, p = 0.001) and EEV CW (mean of 229mL, p = 0.02) increases that were mainly observed in the RCp. No significant changes were found when performing DE RV (deep expiration from residual volume) and ICo RV (Inspiratory contraction from RV). Positive correlations were also observed between the degree of inspiratory contraction during ICo TLC and EEV RCp ( rho = 0.613, p = 0.03) and EIV RCp ( rho = 0.697, p = 0.01) changes. Thixotropy conditioning of inspiratory muscles at an inflated chest wall volume increases EIV CW and EEV CW in the ten subsequent breaths in PD patients. These maneuvers are easy to perform, free of equipment, low-cost, and may help patients improve chest wall volumes during rehabilitation.
Materialart:
Online-Ressource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0275584
DOI:
10.1371/journal.pone.0275584.g001
DOI:
10.1371/journal.pone.0275584.g002
DOI:
10.1371/journal.pone.0275584.g003
DOI:
10.1371/journal.pone.0275584.t001
DOI:
10.1371/journal.pone.0275584.t002
DOI:
10.1371/journal.pone.0275584.t003
DOI:
10.1371/journal.pone.0275584.s001
Sprache:
Englisch
Verlag:
Public Library of Science (PLoS)
Publikationsdatum:
2022
ZDB Id:
2267670-3