In:
Korean Journal of Veterinary Research, The Korean Society of Veterinary Science (KJVR), Vol. 61, No. 3 ( 2021-09-30), p. e21-
Kurzfassung:
Canine T-zone lymphoma (TZL) is a mature T-cell lymphoma in dogs. The diagnosis and sub-classification are impossible without biopsy or immunophenotyping by flow cytometry. An 11-year-old, spayed, female Golden Retriever presented with lymph node enlargement. Clinical examination was consistent with canine multicentric lymphoma. However, immunophenotyping revealed positive for CD3, CD4, CD5, CD8, CD21, TCRαβ, and MHCII but negative for CD34, CD45, CD79a, and TCRγδ. Histopathology revealed lymphocytes expanding to the cortex-preserving architecture and thinning of the nodal capsule, and CD3 positive but PAX-5 negative. Owing to the indolent nature of TZL, careful monitoring approach without clinical intervention was utilized.
Materialart:
Online-Ressource
ISSN:
2466-1384
,
2466-1392
DOI:
10.14405/kjvr.2021.61.e21
Sprache:
Englisch
Verlag:
The Korean Society of Veterinary Science (KJVR)
Publikationsdatum:
2021