In:
LymphoSign Journal, LymphoSign Journal Limited Partnership, Vol. 2, No. 1 ( 2015-03-01), p. 3-19
Abstract:
Immunodeficiencies of most T-cell receptor (TCR) components (TCRID) have been reported in almost 40 patients worldwide who have also, at times, shown signs of autoimmunity. We updated their clinical, immunological, and molecular features with an emphasis on practical diagnosis, as the range of the disorder grows in complexity with new partial defects. Cellular and animal models are also reviewed and in some cases reveal their limitations for predicting TCRID immunopathology.
Type of Medium:
Online Resource
ISSN:
2292-5937
,
2292-5945
DOI:
10.14785/lpsn-2014-0012
Language:
English
Publisher:
LymphoSign Journal Limited Partnership
Publication Date:
2015