In:
cclm, Walter de Gruyter GmbH, Vol. 36, No. 6 ( 1998-06-01), p. 355-359
Abstract:
Immunoassays are widely used for determination of the concentration of steroid hormones. However, obtaining specific anti-steroid monoclonal antibodies remains difficult. We used antibody engineering and phage display methods to change the specificity of an anti-cortisol monoclonal antibody towards estradiol. This work demonstrates that production of recombinant antibodies may be a valuable way of obtaining the high-specificity antibodies required for steroid immunoassays.
Type of Medium:
Online Resource
ISSN:
1434-6621
,
1437-4331
DOI:
10.1515/CCLM.1998.060
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
1998
detail.hit.zdb_id:
1492732-9
SSG:
15,3
