In:
Open Life Sciences, Walter de Gruyter GmbH, Vol. 10, No. 1 ( 2015-2-4)
Abstract:
Background: The extracts of Allium cepa
are known for their medical use: antioxidant, antiinflammatory, antimicrobial, fibrinolytic and antiplatelet
properties. Our study aims to establish, using in vitro tests, the antiplatelet and antioxidant character, the link between
them and the extract acidity, from seven varieties of A. cepa. Methodology: The qualitative and quantitative
presence of polyphenols and anthocyanins in the extracts was determined using UV-Vis and HPLC.
Quantitative determination of the thiosulfinates compounds was calculated using their reaction with
4-mercaptopyridine. Antioxidant character was determined using 3 methods (FC, DPPH and TEAC),
and antiplatelet effect was measured by in vitro tests on platelet rich plasma obtained from human blood.
Principal Findings/Results: The white variety of A. cepa has the most alkaline pH, the largest amount of thiosulfinate compounds and the most powerful
antiplatelet effect, but a very small amount of flavonoids and an antioxidant effect almost nonexistent, in contrast
with red variety of A. cepa which is the opposite. Conclusions/Significance: The white variety of A. cepa had
very high anitiplatelet activity suggesting the potential use of A. cepa extract in treating cardiovascular diseases.
Type of Medium:
Online Resource
ISSN:
2391-5412
DOI:
10.1515/biol-2015-0011
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2015
detail.hit.zdb_id:
2817958-4
SSG:
12
