In:
Heterocyclic Communications, Walter de Gruyter GmbH, Vol. 25, No. 1 ( 2019-05-31), p. 91-97
Abstract:
A series of novel perfluoropropan-2-yl-based quinoline derivatives was designed and synthesized utilizing tebufloquin as the lead compound. The structures of all the newly synthesized compounds were confirmed by spectroscopic data 1 HNMR, MS and elemental analysis. The results of bioassay indicated that these compounds exhibited potent fungicidal activities against Erysiphe graminis . Especially, compound 8c displayed excellent activity with EC 50 value at 1.48 mg / L, which was better than that of the commercialized fungicide --- tebufloquin. The structure-activity relationship for these new compounds was also discussed.
Type of Medium:
Online Resource
ISSN:
2191-0197
DOI:
10.1515/hc-2019-0002
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2019
detail.hit.zdb_id:
2598389-1