In:
Journal of Laboratory Medicine, Walter de Gruyter GmbH, Vol. 45, No. 3 ( 2021-06-25), p. 159-165
Kurzfassung:
Tests for diagnosing infectious diseases (ID-POCT) play a special role among the available point-of-care testing (POCT) methods. Methods A systematic literature search was performed in PubMed. Based on this literature review and our own experience, aspects associated with using molecular biological methods in the diagnostic amplification of pathogen DNA/RNA (nucleic acid testing = NAT) and/or signal amplification were discussed in an interdisciplinary manner. This resulted in the following recommendations for the near-patient use of NAT methods. Results Due to the current rise in the use of near-patient NAT testing (e.g., using disposable cartridges), recommendations are made for their implementation and appropriate clinical use in the hospital setting. Particular emphasis is placed on the analytical quality of the results. Furthermore, internal best-practice rules and selection criteria are proposed to ensure rapid diagnosis. Equally important are a medically valid interpretation of results and compliance with hygiene requirements. These recommendations emphasize that near-patient NAT should always be procured in conjunction with a (preferably) multidisciplinary institution responsible for POCT and knowledge of the test specifications and risks, as well as quality assurance need to be in place before they are carried out. Conclusions These recommendations are intended to improve patient safety and to avoid economically questionable expenditures.
Materialart:
Online-Ressource
ISSN:
2567-9449
,
2567-9430
DOI:
10.1515/labmed-2021-0035
Sprache:
Englisch
Verlag:
Walter de Gruyter GmbH
Publikationsdatum:
2021
ZDB Id:
2909042-8
