In:
Pediatrics, American Academy of Pediatrics (AAP), Vol. 104, No. 1 ( 1999-07-01), p. 113-115
Kurzfassung:
Infantile myofibromatosis is marked by the development of firm, discrete, flesh-colored to purple nodules in skin, muscle, bone, and/or subcutaneous tissues. In cases without visceral involvement, the prognosis is excellent with expected spontaneous regression of nodules in 1 to 2 years. Visceral lesions are associated with significant morbidity and mortality generally within the first few months of life secondary to obstruction of a vital organ, failure to thrive, or infection. Observation. We present a case of congenital myofibromatosis initially presenting as a single, asymptomatic nodule on the midback of an otherwise healthy 1-month-old white boy. Over the subsequent 6 months, the child developed a left-sided head tilt with the formation of additional myofibromas of the skin and musculature, but without visceral involvement. Physical examinations have continued to show age-appropriate growth and development. Conclusion. Clinicians should be aware of this rare but potentially life-threatening entity and consider infantile myofibromatosis in the differential diagnosis of pediatric dermal and subcutaneous nodules, particularly when associated with a new onset of head tilt. Close clinical follow-up is recommended in all cases of infantile myofibromatosis.
Materialart:
Online-Ressource
ISSN:
1098-4275
,
0031-4005
DOI:
10.1542/peds.104.1.113
Sprache:
Englisch
Verlag:
American Academy of Pediatrics (AAP)
Publikationsdatum:
1999
ZDB Id:
1477004-0
