In:
Pediatrics, American Academy of Pediatrics (AAP), Vol. 38, No. 6 ( 1966-12-01), p. 957-965
Abstract:
Clinical, laboratory, and virological data are presented for a series of seven infants with cytomegalic inclusion virus disease who have milder and more varied clinical features than were found in other series. These babies were born within a 15-month period in the Seattle area. Only one patient had the typical picture of fulminant neonatal disease. All patients had jaundice which tended to be prolonged, but in most cases this appeared to be associated with mild hemolytic anemia rather than with obstructive hepatitis. Hepatomegaly was seen in six patients and splenomegaly in four. Thrombocytopenic hemorrhagic phenomena occurred in three patients. Two babies had Rh incompatibility associated with obstructive hepatitis, suggesting that cytomegalovirus infection may be an occasional factor in the liver disease in such patients. These patients have been followed for from 2½ to 19½ months. Six patients have been chronic excretors of virus. One patient has microcephaly and spastic hemiparesis, and another is definitely retarded. There were no cases of choroidoretinitis, intracranial calcifications, or seizure disorders.
Type of Medium:
Online Resource
ISSN:
0031-4005
,
1098-4275
DOI:
10.1542/peds.38.6.957
Language:
English
Publisher:
American Academy of Pediatrics (AAP)
Publication Date:
1966
detail.hit.zdb_id:
1477004-0
