In:
Arquivos Brasileiros de Endocrinologia & Metabologia, FapUNIFESP (SciELO), Vol. 48, No. 3 ( 2004-06), p. 406-413
Kurzfassung:
In addition to stimulating body growth, growth or somatotrophic hormone plays an important role in metabolism, body composition, lipid profile, cardiovascular status and longevity. Its control is multiregulated by hormones, metabolites and hypothalamic peptides. Obtained data of the isolated growth hormone deficiency (IGHD) after the description of the IVS1+1G®A GHRH receptor gene mutation in individuals of Itabaianinha County are reviewed. New perspectives about the growth hormone resistance model, the importance of GHRH in the control of GH secretion, the frequency of GHRH-R gene mutations, the diagnostic relevance of IGF-I and the metabolic, cardiovascular and quality of life findings are approached.
Materialart:
Online-Ressource
ISSN:
0004-2730
DOI:
10.1590/S0004-27302004000300013
Sprache:
Unbekannt
Verlag:
FapUNIFESP (SciELO)
Publikationsdatum:
2004
ZDB Id:
2053068-7
