In:
Russian Journal of Oncology, ECO-Vector LLC, Vol. 27, No. 1 ( 2023-03-08), p. 29-36
Abstract:
Diffuse large B-cell lymphoma (DLBCL) is the most common variant of non-Hodgkins lymphoma and accounts for 3060% of all non-Hodgkins lymphomas, with increasing incidence increases with age. Currently, the prognosis is assessed using the International Prognostic Index. In recent years, in all European regions, there has been a significant improvement in survival in DLBCL due to the addition of rituximab to standard chemotherapy (CHOP protocol). However, despite significant advances in treatment, long-term remission is only achieved in half of the patients. Laryngeal lesions with this variant of lymphomas is described only in a few articles. There is evidence of various chemotherapeutic regimens effective in this type of lymphoma; in some publications, the authors suggest the use of radiation therapy. The article presents a clinical case of successful treatment of a patient (chemotherapy + radiation therapy) with diffuse large B-cell lymphoma with laryngeal involvement. with resulting remission. In addition, a review of the literature describing the most common types of lymphomas is presented. The authors set a goal to raise the awareness of physicians about a rare histological variant of laryngeal tumors with a rapid increase in clinical manifestations and the development of life-threatening conditions.
Type of Medium:
Online Resource
ISSN:
2412-9119
,
1028-9984
DOI:
10.17816/onco109580-1686329
DOI:
10.17816/onco109580-1686330
DOI:
10.17816/onco109580-1686331
Language:
Unknown
Publisher:
ECO-Vector LLC
Publication Date:
2023