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    In: Actual problems in dentistry, TIRAZH Publishing House, Vol. 19, No. 2 ( 2023-08-21), p. 51-58
    Abstract: Subject. The subject of the study is the anti-inflammatory and anti-plaque effect of spray against gum bleeding «DentaBalance®» synbiotic complex in the treatment of chronic simple marginal gingivitis. Objectives. The aim of the study is to conduct a clinical evaluation of spray against gum bleeding «DentaBalance®» synbiotic complex in the complex treatment and hygienic oral care in patients with chronic simple marginal gingivitis (CSMG). Methodology. A pilot open prospective non-randomized multicenter study was conducted to evaluate the anti-inflammatory and anti-plaque effects of spray against gum bleeding «DentaBalance®» synbiotic complex in the treatment of CSMG. The sample consisted of 99 patients aged 20–33 years with CSMG in localized or generalized form, who used spray against gum bleeding «DentaBalance®» synbiotic complex including lysate from Streptococcus Thermophilus and prebiotics 2 times a day for 4 weeks on their own in-home therapy mode. The condition of the gum and oral hygiene was evaluated clinically and objectified indexically (BoP, OHI-S) at 3 observation points: initially, 7 and 28 days after the start of observation. Results. Based on the results of a short-term clinical study, a reliable anti-inflammatory and anti-plaque effect of spray against gum bleeding «DentaBalance®» synbiotic complex was determined. The anti-inflammatory effect was objectified by a significant decrease in the BoP index by 44.7% on the 7th day and by 33.5% additionally on the 28th day of observation. The cleansing effect on the OHI-S index increased from 16.87% on the 7th day of observation to 55.41% at its final stage. The expediency of using spray against gum bleeding «DentaBalance®» synbiotic complex in the complex treatment of CSMG is pathogenetically substantiated, the advantages and prospects of its use in periodontal practice are established. Conclusion. The effectiveness and safety of the spray against gum bleeding «DentaBalance®» synbiotic complex including lysate from Streptococcus Thermophilus and prebiotics for hygienic oral care and effective relief of gum inflammation symptoms in patients with CSMG has been pathogenetically substantiated and clinically proven.
    Type of Medium: Online Resource
    ISSN: 2077-7566 , 2412-9461
    Uniform Title: КЛИНИЧЕСКАЯ ОЦЕНКА ЭФФЕКТИВНОСТИ ЛЕЧЕНИЯ ХРОНИЧЕСКОГО ПРОСТОГО МАРГИНАЛЬНОГО ГИНГИВИТА С ИСПОЛЬЗОВАНИЕМ СПРЕЯ ОТ КРОВОТОЧИВОСТИ ДЕСЕН «ДЕНТАБАЛАНС®» — СИНБИОТИЧЕСКОГО КОМПЛЕКСА, СОДЕРЖАЩЕГО STREPTOCOCUS THERMOPHILUS ЛИЗАТ И ПРЕБИОТИКИ (МНОГОЦЕНТРОВОЕ КЛИНИЧЕСКОЕ ИССЛЕДОВАНИЕ)
    URL: Issue
    Language: English , Russian
    Publisher: TIRAZH Publishing House
    Publication Date: 2023
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