In:
American Journal of Public Health, American Public Health Association, Vol. 104, No. 8 ( 2014-08), p. e43-e50
Kurzfassung:
We examined the relationship between serum 25-hydroxyvitamin D (25[OH]D) and all-cause mortality. We searched biomedical databases for articles that assessed 2 or more categories of 25(OH)D from January 1, 1966, to January 15, 2013. We identified 32 studies and pooled the data. The hazard ratio for all-cause mortality comparing the lowest (0–9 nanograms per milliliter [ng/mL]) to the highest ( 〉 30 ng/mL) category of 25(OH)D was 1.9 (95% confidence interval = 1.6, 2.2; P 〈 .001). Serum 25(OH)D concentrations less than or equal to 30 ng/mL were associated with higher all-cause mortality than concentrations greater than 30 ng/mL (P 〈 .01). Our findings agree with a National Academy of Sciences report, except the cutoff point for all-cause mortality reduction in this analysis was greater than 30 ng/mL rather than greater than 20 ng/mL.
Materialart:
Online-Ressource
ISSN:
0090-0036
,
1541-0048
DOI:
10.2105/AJPH.2014.302034
Sprache:
Englisch
Verlag:
American Public Health Association
Publikationsdatum:
2014
ZDB Id:
2054583-6