In:
Current Medicinal Chemistry, Bentham Science Publishers Ltd., Vol. 30, No. 26 ( 2023-08), p. 2996-3023
Abstract:
Treatment of various diseases, especially cancer treatment, includes the potential
use of different types of nanoparticles and nanostructures as drug carriers. However, searching for less toxic and more efficient therapy requires further progress, wherein recent
developments in medicine increasingly include the use of various advanced nanostructures. Their more successful application might be achieved by leveling imbalances between
the potentiality of different nanostructures and the demands required for their safe use. Biocompatibility, biodegradability, prolonged circulation time and enhanced accumulation
and uptake by cells are some of the key preconditions for their usage in efficient drug delivery. Thanks to their greatly tunable functions, they are major building
blocks for manufacturing novel materials. Nevertheless, given that their toxicity is questionable, their practical application is challenging. Hereof, before entering the sphere of
human consumption, it is of critical importance to perform more studies regarding their toxicity and drug distribution. This review emphasizes recent advances in nanomedicine,
employing different kinds of conventionally used nanoparticles as well as novel nanoparticles and nanostructures. Special emphasis is placed on micro/nanomotors (MNMs), discussing
their opportunities, limitations, challenges and possible applications in drug delivery and outlining some perspectives in the nanomedicine area.
Type of Medium:
Online Resource
ISSN:
0929-8673
DOI:
10.2174/0929867329666220821193938
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
2023
SSG:
15,3
