In:
Current Medical Imaging Reviews, Bentham Science Publishers Ltd., Vol. 18, No. 14 ( 2022-12), p. 1517-1525
Abstract:
β-blockers are widely used for lowering heart rate (HR) during coronary computed
tomography angiography (CCTA); however, they should be used with caution for patients with heart failure as they may have a negative inotropic effect. Objective: To clarify the effects of β-blockers (oral and intravenous injection) on cardiac function using
CCTA. Methods: A total of 244 patients (men: women = 166: 78; mean age, 64.4 years old) suspected of having
ischemic cardiac disease and had undergone echocardiography within 3 months before and after CCTA were included in the study. Systematic errors in ejection fraction (EF) were corrected by calculating
ΔEF from the EF difference between echocardiography and CCTA in patients not using β- blockers. Univariate and multivariate analyses were performed for factors affecting ΔEF. In addition,
HR between, before, and during CCTA were compared by Wilcoxon’s test. Results: Temporary oral or intravenous administration of β-blockers at the CCTA had no significant
effects on EF (p = 0.70), whereas HR was significantly decreased (p 〈 0.001). However, regular administration
of β-blockers increases the EF on CCTA. Conclusion: The administration of β-blockers immediately before CCTA affects HR but not EF. Premedication
with β-blockers can be safely used for patients who undergo CCTA, and CCTA is useful for EF evaluation, independent of the use of β-blockers.
Type of Medium:
Online Resource
ISSN:
1573-4056
DOI:
10.2174/1573405618666220518104929
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
2022
