In:
The Open Bioinformatics Journal, Bentham Science Publishers Ltd., Vol. 2, No. 1 ( 2008-07-25), p. 28-36
Kurzfassung:
In this work we present an application for integrating and analyzing life science data using a biomedical data
warehouse system and tools developed in-house enabling knowledge discovery tasks. Knowledge discovery is known as a process where different steps have to be coupled in order to solve a specified question. In order to create such a combination
of steps, a data miner using our in-house developed knowledge discovery tool KD 3 is able to assemble functional objects
to a data mining workflow. The generated workflows can easily be used for ulterior purposes by only adding new data and parameterizing the functional objects in the process. Workflows guide the performance of data integration and
aggregation tasks, which were defined and implemented using a public available open source tool. To prove the concept of our application, intelligent query models were designed and tested for the identification of genotype-phenotype correlations
in Marfan Syndrome. It could be shown that by using our application, a data miner can easily develop new knowledge discovery algorithms that may later be used to retrieve medical relevant information by clinical researchers.
Materialart:
Online-Ressource
ISSN:
1875-0362
DOI:
10.2174/1875036200802010028
Sprache:
Englisch
Verlag:
Bentham Science Publishers Ltd.
Publikationsdatum:
2008
ZDB Id:
2413371-1
