In:
Biomarkers in Medicine, Future Medicine Ltd, Vol. 10, No. 4 ( 2016-04), p. 367-373
Abstract:
Aim: Platelet-to-lymphocyte ratio (PLR) was proposed as a novel indirect marker of inflammation. We aimed to evaluate the relationship between PLR and aortic stenosis (AS). Patients & methods: The study population included 453 patients of which 98 patients with severe AS, 206 patients with mild-to-moderate AS and 149 patients as control. Results: PLR was significantly increased in parallel to the severity of AS (p 〈 0.001). There was significant positive correlation between PLR and maximum, and mean systolic transaortic gradient (all p 〈 0.001). Also, PLR was correlated with C-reactive protein and neutrophil-to-lymphocyte ratio (all p 〈 0.001) and PLR was independently associated with the presence of AS (p 〈 0.001). Conclusion: We found a significant relationship between PLR and AS.
Type of Medium:
Online Resource
ISSN:
1752-0363
,
1752-0371
DOI:
10.2217/bmm-2015-0016
Language:
English
Publisher:
Future Medicine Ltd
Publication Date:
2016