In:
Future Oncology, Future Medicine Ltd, Vol. 14, No. 12 ( 2018-05), p. 1187-1196
Kurzfassung:
Aim: To evaluate the prognostic value of preoperative to postoperative neutrophil-to-lymphocyte ratio changes (ΔNLR) in patients undergoing surgical resection for colorectal cancer. Patients & methods: Data of 135 such patients managed at the Shandong Cancer Hospital and Institute were retrospectively analyzed. Clinicopathologic factors, overall survival (OS) and disease-free survival (DFS) were assessed using Kaplan–Meier curves and Cox regression models. Results: In the multivariate analysis, preoperative NLR (p = 0.002) and ΔNLR (p = 0.037) independently predicted OS, but preoperative NLR (p = 0.141) and ΔNLR (p = 0.297) were not significant prognosticators for DFS. Conclusion: Our results demonstrated the prognostic value of the ΔNLR in predicting OS in patients undergoing surgical resection for colorectal cancer. However, ΔNLR could not predict DFS.
Materialart:
Online-Ressource
ISSN:
1479-6694
,
1744-8301
DOI:
10.2217/fon-2017-0659
Sprache:
Englisch
Verlag:
Future Medicine Ltd
Publikationsdatum:
2018
