In:
Kidney Research and Clinical Practice, The Korean Society of Nephrology, Vol. 41, No. 1 ( 2022-01-31), p. 43-57
Kurzfassung:
Background: Diabetic nephropathy (DN) can affect quality of life (QoL) because it requires arduous lifelong management. This study analyzed QoL differences between DN patients and patients with other chronic kidney diseases (CKDs). Methods: The analysis included subjects (n = 1,766) from the KNOW-CKD (Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease) cohort who completed the Kidney Disease Quality of Life Short Form questionnaire. After implementing propensity score matching (PSM) using factors that affect the QoL of DN patients, QoL differences between DN and non-DN participants were examined. Results: Among all DN patients (n = 390), higher QoL scores were found for taller subjects, and lower scores were found for those who were unemployed or unmarried, received Medical Aid, had lower economic status, had higher platelet counts or alkaline phosphatase levels, or used clopidogrel or insulin. After PSM, the 239 matched DN subjects reported significantly lower patient satisfaction (59.9 vs. 64.5, p = 0.02) and general health (35.3 vs. 39.1, p = 0.04) than the 239 non-DN subjects. Scores decreased in both groups during the 5-year follow-up, and the scores in the work status, sexual function, and role-physical domains were lower among DN patients than non-DN patients, though those differences were not statistically significant. Conclusion: Among the DN subjects, socioeconomic factors were strong risk factors for impaired QoL, as were high platelet counts, high alkaline phosphatase levels, and clopidogrel and insulin use. Clinicians should keep in mind that the QoL of DN patients might decrease in some domains compared with that in patients with other CKDs.
Materialart:
Online-Ressource
ISSN:
2211-9140
DOI:
10.23876/j.krcp.21.068
Sprache:
Englisch
Verlag:
The Korean Society of Nephrology
Publikationsdatum:
2022
ZDB Id:
2656420-8
