In:
American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 62, No. 1 ( 2001-01-01), p. 43-47
Abstract:
Objective —To evaluate the clinical and histologic
effects of repeated intraosseous (IO) needle placement in domestic pigs and determine whether blood
and serum obtained intraosseously could be used for CBC and biochemical analyses. Animals —5 healthy 10-week-old pigs. Procedure —An IO needle was placed in the proximomedial
region of the tibia of anesthetized pigs every other week for 2 months, and IO blood was
obtained for CBC and serum biochemical analyses. Results were compared with those obtained for blood
collected at the same time from the auricular vein. Two weeks after the final samples were obtained,
pigs were euthanatized and tibias were processed for histologic examination. Results —Clinical abnormalities, including lameness,
were not detected following IO needle placement. Histologic examination revealed only mild multifocal
periosteal fibrosis and slight thickening of the periosteum without evidence of osteomyelitis. Chloride,
creatinine, glucose, total protein, sodium, and BUN concentrations, alanine transaminase and gamma glutamyl
transpeptidase activities, RBC count, mean corpuscular volume, and Hct did not significantly differ
between IO and venous samples. However, aspartate transaminase activity, potassium, hemoglobin, and
mean corpuscular hemoglobin concentrations, mean corpuscular hemoglobin, and platelet and WBC
counts were significantly different. Conclusion and Clinical Relevance —Repeated
placement of IO needles may be a safe and clinically useful method to obtain serial blood samples from
domestic pigs, particularly when other vascular sites are not accessible. Intraosseous blood can be used
for many of the tests comprising CBC and serum biochemical analyses. ( Am J Vet Res 2001;62:43–47)
Type of Medium:
Online Resource
ISSN:
0002-9645
DOI:
10.2460/ajvr.2001.62.43
Language:
Unknown
Publisher:
American Veterinary Medical Association (AVMA)
Publication Date:
2001
detail.hit.zdb_id:
2056942-7
SSG:
22
