In:
International Journal of Research in Pharmaceutical Sciences, GP Innovations Pvt. Ltd., Vol. 11, No. 3 ( 2020-07-08), p. 3204-3211
Abstract:
Liquid chromatographic offers efficient analyte separation employing high pressure pumps. The reversed phase high performance liquid chromatography (RP-HPLC) is widely utilized in the purity testing and quantitative determination of pharmaceuticals and neutraceuticals. The limitations of traditional liquid chromatography such as particle size, resolution and selectivity demanded for the developments and Waters Corporation developed ultraperformance liquid chromatography (UPLC). Ultrafast liquid chromatography (UFLC) is another milestone, which offers faster and efficient separation. Multidimensional UHPLC provides separation of complex molecules. The particle size decrease enhances the resolution of LC separation. Ethylene bridged hybrid (BEH), Charged surface hybrid (CSH) and Peptide separation technology (PST) offer better performance in. The amalgamation of chromatographic and spectroscopic detectors namely fluorescence detector (FD) and mass spectrometry (MS) provides efficient separation. Liquid chromatography (LC) offers the analysis of pharmaceuticals, biological, food materials, and natural products. This review covers technologies and recent pharmaceutical and biomedical applications of liquid chromatography technologies
Type of Medium:
Online Resource
ISSN:
0975-7538
DOI:
10.26452/ijrps.v11i3
DOI:
10.26452/ijrps.v11i3.2449
Language:
Unknown
Publisher:
GP Innovations Pvt. Ltd.
Publication Date:
2020
