In:
Surgical Case Reports, Science Repository OU
Kurzfassung:
Polyurethane is a medical material, which has excellent physical properties and high mechanical
compatibility. At present, one of the most effective application methods for antibacterial bacterial biofilm is to combine polyurethane with nano-silver, so that the polyurethane material itself has bactericidal
performance and finally plays a good antibacterial effect. From August 2011 to January 2014, 75 patients with crush injury or avulsion injury who had difficulty healing were randomly divided into 5 groups.
Results: Comparison of colony count results of different concentrations of nano-silver polyurethane; comparison of colony count results of two groups in vitro; comparison of anticoagulant degree and
determination of whole blood coagulation time; comparison of coagulation routine examination results of two groups; comparison of epithelial growth factor levels at different time after treatment; comparison of tumor necrosis factor- a levels at different time after treatment between two groups; comparison of change
times, visual analogue score of pain during treatment and hospitalization time of two groups; comparison of white blood cell count of two groups of polyurethane patients within 1 week; comparison of clinical
efficacy between two groups. Conclusion: The medical material containing nano-silver polyurethane is a good bacteriostatic biomaterial,
which can inhibit common iatrogenic pathogens in vitro. The application of 5% nano-silver polyurethane medical material to open wound, especially in patients with avulsion and crush injury in orthopaedics, can
inhibit the growth of common hospital pathogenic bacteria. can significantly reduce the level of tumor necrosis factor- a in the wound, reduce the local inflammatory response, and can significantly improve the
clinical effect of the treatment of complex wounds, which is worthy of clinical promotion.
Materialart:
Online-Ressource
ISSN:
2613-5965
,
2613-5965
DOI:
10.31487/j.SCR.2020.06.22
Sprache:
Unbekannt
Verlag:
Science Repository OU
Publikationsdatum:
2020