In:
Journal of Health Sciences and Medicine, Journal of Health Sciences and Medicine, Vol. 4, No. 5 ( 2021-09-05), p. 746-751
Abstract:
Aim: Environmental exposure and maternal nutrition are vital for placental and fetal development during pregnancy. Essential elements such as Zinc (Zn), Copper (Cu) and Selenium (Se) are important elements that are needed for human growth and development. Research indicates that methylated arginines play a key role in pregnancy and offspring outcomes. The aim of the study was to compare the placental tissue levels of trace elements and methylated arginines. In addition, to evaluate this placental trace elements and methylated arginine levels in terms of placental and birth weight. Material and Methods: This is a case-control study with 133 pregnant women. Two groups were formed: women with higher risk of exposure to chemicals (working in chemistry, metal and other industrial sectors) and those with no risk of exposure to hazardous chemicals (house wives and working in other non-hazardous workplaces). Placenta Zn, Cu, Se, ADMA, SDMA, arginine, citrulline, homoarginine and L-NMMA levels were investigated. Results: There was a positive correlation between birth weight with Cu, L-NMMA, total methylarginines; there was a negative relationship between birth weight and ADMA, SDMA, arginine, citrulline. However, no statistically significant relationship was found between trace elements such as Zn, Cu and Se with methylated arginines, except for L-NMMA (r=0.178; p
Type of Medium:
Online Resource
ISSN:
2636-8579
DOI:
10.32322/jhsm.962489
Language:
Unknown
Publisher:
Journal of Health Sciences and Medicine
Publication Date:
2021
detail.hit.zdb_id:
2944547-4
