In:
Frontiers in Endocrinology, Frontiers Media SA, Vol. 13 ( 2023-1-12)
Abstract:
To assess abdominal fat deposition and lumbar vertebra with iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL-IQ) and investigate their correlation with menopausal status. Materials and Methods Two hundred forty women who underwent routine abdominal MRI and IDEAL-IQ between January 2016 and April 2021 were divided into two cohorts (first cohort: 120 pre- or postmenopausal women with severe fatty livers or without fatty livers; second cohort: 120 pre- or postmenopausal women who were obese or normal weight). The fat fraction (FF) values of the liver (FF liver ) and lumbar vertebra (FF lumbar ) in the first group and the FF values of subcutaneous adipose tissue (SAT) (FF SAT ) and FF lumbar in the second group were measured and compared using IDEAL-IQ. Results Two hundred forty women were evaluated. FF lumbar was significantly higher in both pre- and postmenopausal women with severe fatty liver than in patients without fatty livers (premenopausal women: p & lt; 0.001, postmenopausal women: p & lt; 0.001). No significant difference in the FF lumbar was observed between obese patients and normal-weight patients among pre- and postmenopausal women (premenopausal women: p = 0.113, postmenopausal women: p = 0.092). Significantly greater lumbar fat deposition was observed in postmenopausal women than in premenopausal women with or without fatty liver and obesity ( p & lt; 0.001 for each group). A high correlation was detected between FF liver and FF lumbar in women with severe fatty liver (premenopausal women: r=0.76, p & lt;0.01; postmenopausal women: r=0.82, p & lt;0.01). Conclusion Fat deposition in the vertebral marrow was significantly associated with liver fat deposition in postmenopausal women.
Type of Medium:
Online Resource
ISSN:
1664-2392
DOI:
10.3389/fendo.2022.1099919
DOI:
10.3389/fendo.2022.1099919.s001
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2023
detail.hit.zdb_id:
2592084-4
