In:
Frontiers in Endocrinology, Frontiers Media SA, Vol. 13 ( 2022-2-10)
Abstract:
To compare the effects of real-time and retrospective flash glucose monitoring (FGM) on daily glycemic control and lifestyle in patients with type 2 diabetes on premix insulin therapy. Methods and Results A total of 172 patients using premix insulin, with HbA1c ≥ 7.0% (56 mmol/mol), or the time below the target (TBR) ≥ 4%, or the coefficient of variation (CV) ≥36% during the screening period, were randomly assigned to retrospective FGM (n = 89) or real-time FGM group (n = 83). Another two retrospective or real-time 14-day FGMs were performed respectively, 1 month apart. Both groups received educations and medication adjustment after each FGM. Time in range (3.9~10.0 mmol/l, TIR) increased significantly after 3 months in the real-time FGM group (6.5%) compared with the retrospective FGM group (-1.1%) ( p = 0.014). HbA1c decreased in both groups (both p & lt; 0.01). Real-time FGMs increased daily exercise time compared with the retrospective group ( p = 0.002). Conclusions Real-time FGM with visible blood glucose improves daily glycemic control and diabetes self-care behaviors better than retrospective FGM in patients with type 2 diabetes on premix insulin therapy. Clinical Trial Registration https://clinicaltrials.gov/NCT04847219 .
Type of Medium:
Online Resource
ISSN:
1664-2392
DOI:
10.3389/fendo.2022.832102
DOI:
10.3389/fendo.2022.832102.s001
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2022
detail.hit.zdb_id:
2592084-4
