In:
Frontiers in Integrative Neuroscience, Frontiers Media SA, Vol. 15 ( 2021-8-16)
Abstract:
The miniscope system is one of the calcium (Ca 2+ ) imaging tools with small size and lightweight and can realize the deep-brain Ca 2+ imaging not confined to the cerebral cortex. Combining Ca 2+ imaging and electrophysiology recording has been an efficient method for extracting high temporal-spatial resolution signals in the brain. In this study, a particular electrode probe was developed and assembled on the imaging lens to modify the miniscope system. The electrode probe can be tightly integrated into the lens of the miniscope without increasing the volume, weight, and implantation complexity. In vivo tests verified that the proposed modified system has realized the simultaneous recording of Ca 2+ signals and local field potential (LFP) signal in the hippocampus CA1 region of an adult mouse.
Type of Medium:
Online Resource
ISSN:
1662-5145
DOI:
10.3389/fnint.2021.682019
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2021
detail.hit.zdb_id:
2452962-X
