In:
Antioxidants, MDPI AG, Vol. 13, No. 9 ( 2024-08-30), p. 1065-
Kurzfassung:
Stroke is one of the most significant causes of death and long-term disability globally. Overproduction of reactive oxygen species by NADPH oxidase (NOX) plays an important role in exacerbating oxidative stress and causing neuronal damage after a stroke. There is growing evidence that NOX inhibition prevents ischemic injury and that the role of NOX in brain damage or recovery depends on specific post-stroke phases. In addition to studies on post-stroke neuroprotection by NOX inhibition, recent reports have also demonstrated the role of NOX in stroke recovery, a critical process for brain adaptation and functional reorganization after a stroke. Therefore, in this review, we investigated the role of NOX in stroke recovery with the aim of integrating preclinical findings into potential therapeutic strategies to improve stroke recovery.
Materialart:
Online-Ressource
ISSN:
2076-3921
DOI:
10.3390/antiox13091065
Sprache:
Englisch
Verlag:
MDPI AG
Publikationsdatum:
2024
ZDB Id:
2704216-9
SSG:
15,3
