In:
Cells, MDPI AG, Vol. 12, No. 2 ( 2023-01-11), p. 287-
Abstract:
The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be therapeutically beneficial. Herein, we disclose SGC-CAMKK2-1, a selective chemical probe that targets CAMKK2.
Type of Medium:
Online Resource
ISSN:
2073-4409
DOI:
10.3390/cells12020287
Language:
English
Publisher:
MDPI AG
Publication Date:
2023
detail.hit.zdb_id:
2661518-6