In:
Coatings, MDPI AG, Vol. 7, No. 7 ( 2017-07-06), p. 96-
Kurzfassung:
Poly(3,4-ethylenedioxythiophene) (PEDOT) doped with poly (styrene sulfonate) (PSS) has a variety of chemical and biomedical applications. Additionally, chitosan has been extensively used in industrial and medical fields. However, whether chitosan could be incorporated into conducting polymers of PEDOT/PSS is not clear. In this study, the PEDOT/PSS/chitosan coatings were electrochemically polymerized on the surface of 0.5 mm platinum (Pt) electrodes and the properties of electrochemical cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) of the PEDOT/PSS/chitosan-coated electrodes were investigated. Furthermore, PEDOT/PSS/chitosan-coated electrodes used for electrochemical bio-sensing, using dexamethasone (Dex) as a model bio-sensing material, were examined. The results demonstrated that PEDOT/PSS/chitosan-coated electrodes were stable in phosphate-buffered saline (PBS) solution. The electrochemical CV curve areas, reflecting the charge delivery capacity, and the EIS of the PEDOT/PSS/chitosan-coated electrodes were sensitive to Dex, and the good linearity can be obtained between CV curve areas, the EIS and the concentration of Dex. In addition, electrochemical sensitivity of the PEDOT/PSS/chitosan-coated electrodes to Dex was much higher than ultraviolet (UV) spectroscopy detection. All these results revealed that the PEDOT/PSS/chitosan-coated electrodes can be electrochemical polymerized and used for electrochemical bio-sensing.
Materialart:
Online-Ressource
ISSN:
2079-6412
DOI:
10.3390/coatings7070096
Sprache:
Englisch
Verlag:
MDPI AG
Publikationsdatum:
2017
ZDB Id:
2662314-6
