In:
Toxics, MDPI AG, Vol. 8, No. 3 ( 2020-09-02), p. 66-
Abstract:
The role of inorganic elements as risk factors for stroke has been suggested. We designed a case-control study to explore the role of 45 inorganic elements as factors associated with stroke in 92 patients and 83 controls. Nineteen elements were detected in 〉 80% of patients and 21 were detected in 〉 80% of controls. Blood level of lead was significantly higher among patients (11.2 vs. 9.03 ng/mL) while gold and cerium were significantly higher among controls (0.013 vs. 0.007 ng/mL; and 18.0 vs. 15.0 ng/mL). Lead was associated with stroke in univariate and multivariate analysis (OR = 1.65 (95% CI, 1.09–2.50) and OR = 1.91 (95% CI, 1.20–3.04), respectively). Gold and cerium showed an inverse association with stroke in multivariate analysis (OR = 0.81 (95% CI, 0.69–0.95) and OR = 0.50 (95% CI, 0.31–0.78)). Future studies are needed to elucidate the potential sources of exposure and disclose the mechanisms of action.
Type of Medium:
Online Resource
ISSN:
2305-6304
DOI:
10.3390/toxics8030066
Language:
English
Publisher:
MDPI AG
Publication Date:
2020
detail.hit.zdb_id:
2733883-6