In:
Pharmacia, Pensoft Publishers, Vol. 70, No. 1 ( 2023-01-04), p. 1-7
Abstract:
Objectives : The aim of this research is to examine the effects of fructose-drinking on the plasma levels of appetite-regulating hormones insulin, leptin and ghrelin in male and female rats. Methods : Mature Wistar rats were divided as follows: two control groups - male (CM) and female (CF); two fructose-drinking groups - male (FDM) and female (FDF), received 15% fructose solution. The experiment lasted 11 weeks. At the end, insulin, leptin and ghrelin levels as well as lipid and glucose profile were assessed. Results : Plasma concentrations of the examined hormones were elevated in fructose-drinking groups. However, in the FDM group only the leptin levels were significantly increased compared to the control. In the FDF group, all three appetite-regulating hormones showed the highest concentrations in comparison to the other groups. Conclusion : Sex hormones may affect the appetite-regulation signals and could be a factor contributing to degree of metabolic changes caused by long-term fructose overconsumption.
Type of Medium:
Online Resource
ISSN:
2603-557X
,
0428-0296
DOI:
10.3897/pharmacia.70.e87712
DOI:
10.3897/pharmacia.70.e87712.figure1
DOI:
10.3897/pharmacia.70.e87712.figure2
DOI:
10.3897/pharmacia.70.e87712.figure3
DOI:
10.3897/pharmacia.70.e87712.figure4
DOI:
10.3897/pharmacia.70.e87712.figure5
DOI:
10.3897/pharmacia.70.e87712.figure6
DOI:
10.3897/pharmacia.70.e87712.figure7
DOI:
10.3897/pharmacia.70.e87712.figure8
Language:
Unknown
Publisher:
Pensoft Publishers
Publication Date:
2023
detail.hit.zdb_id:
3010005-7
SSG:
15,3