In:
The Journal of Immunology, The American Association of Immunologists, Vol. 122, No. 1 ( 1979-01-01), p. 44-48
Abstract:
The N-terminal sequences from heavy variable regions of 47 myeloma proteins of the NZB mouse have been analyzed. Sixteen of these VH regions have unblocked α amino groups and have been analyzed over their N-terminal 20 residues by automatic sequence analysis. These sequence data along with the antigen-binding profiles and immunoglobulin class distribution are compared with comparable data from BALB/c myeloma proteins. These comparisons suggest that the NZB and BALB/c populations of myeloma proteins are distinct from one another. The genetic implications of this conclusion are discussed.
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.122.1.44
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
1979
detail.hit.zdb_id:
1475085-5
