In:
The Journal of Immunology, The American Association of Immunologists, Vol. 127, No. 4 ( 1981-10-01), p. 1335-1339
Kurzfassung:
The genetic characteristics, surface markers, and mechanisms of action of early-acting, mitomycin-resistant, MLR suppressor T cells from multiparous mouse spleens were studied in MLR of various strain combinations. The cell activity appears to be genetically restricted at the suppressor/reactive cell level, and the major restriction occurs via the IC subregion. However, C3H.OL recombinant pointed toward a possible minor requirement for S-G subregion syngenicity. The suppressor T cell was characterized as an Ia+, Ly1-, Ly2+ subset. The use of Karush double chambers as well as of supernatants of regulated MLR provided evidence that the suppressor cells act via soluble product(s).
Materialart:
Online-Ressource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.127.4.1335
Sprache:
Englisch
Verlag:
The American Association of Immunologists
Publikationsdatum:
1981
ZDB Id:
1475085-5
