In:
The Journal of Immunology, The American Association of Immunologists, Vol. 93, No. 2 ( 1964-08-01), p. 319-330
Abstract:
The mechanism of rabbit serum bactericidal action on S. typhi 0 901 sensitized with immune antibody has been studied. The bactericidal reaction was separated into three subsequent intermediate reaction steps. An intermediate phase sensitive to MgNa2EDTA and to Na3·HEDTA is followed by a phase sensitive to Na3HEDTA alone. A third phase is reactive in the presence of both MgNa2EDTA and Na3·HEDTA and was identified as the reaction of C′3, as defined in the hemolytic system. All details of the bactericidal reaction tested follow the rules derived for C′ in studies on the hemolytic system. The laws valid for C′ in immune hemolysis seem to apply also for serum bactericidal action on sensitized S. typhi.
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.93.2.319
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
1964
detail.hit.zdb_id:
1475085-5
