In:
Therapeutic Delivery, Future Science Ltd, Vol. 4, No. 2 ( 2013-02), p. 225-237
Abstract:
Many prodrug reviews describe specific examples of the successful application of prodrug technology to produce blockbuster drugs, such as simvastatin, omeprazole, acyclovir and enalapril. These reviews are helpful to understand the previous success stories and case histories of prodrug technology. The aim of the current review seeks to more clearly define quantitative trends in the changes in the physicochemical property parameters between the successful prodrug and the active parent molecule. This information can serve to guide medicinal chemists toward more successful pharmaceutical prodrugs in the future.
Type of Medium:
Online Resource
ISSN:
2041-5990
,
2041-6008
Language:
English
Publisher:
Future Science Ltd
Publication Date:
2013
SSG:
15,3
