In:
The American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, Vol. 105, No. 3 ( 2021-09-15), p. 688-691
Abstract:
Strongyloides stercoralis affects more than half a billion people worldwide, and hyperinfection in immunocompromised patients can be fatal. Elimination of this neglected tropical disease requires field-applicable diagnostic tools. We conducted a laboratory evaluation of a lateral flow rapid dipstick test (SsRapid™) using sera samples from a Strongyloides -endemic area in northeast Thailand. Group 1 was S. stercoralis -positive and larvae- and/or antibody-positive (according to the IgG ELISA) ( N = 100). Group 2 had negative fecal examination and IgG ELISA results ( N = 25). Group 3 had other parasitic infections and negative IgG ELISA results ( N = 25). The results showed good diagnostic sensitivity (82%) and excellent specificity (96%). Suggested improvements in the SsRapid™ test include increased diagnostic sensitivity and conversion to the more robust cassette format. Field studies should be performed as well.
Type of Medium:
Online Resource
ISSN:
0002-9637
,
1476-1645
DOI:
10.4269/ajtmh.21-0317
Language:
Unknown
Publisher:
American Society of Tropical Medicine and Hygiene
Publication Date:
2021
detail.hit.zdb_id:
1491674-5
