In:
Journal of Medicine and Palliative Care, Journal of Medicine and Palliative Care, Vol. 1, No. 4 ( 2020-12-18), p. 103-108
Abstract:
Aim: In this study, we aimed to analyze patients with a diagnosis of acute hypercapnic respiratory failure (AHRF) who responded to noninvasive mechanical ventilation (NIMV) in the intensive care unit (ICU) in the first hours but developed severe respiratory acidosis again soon after switching to nasal oxygen. Material and Method: Between January 2009 and April 2010, data of 139 patients who were followed up in the ICU due to AHRF (pH 45 mmHg) and responded NIMV treatment in the first 1-4 hours, were analyzed retrospectively. Patients were divided into two groups as those with rebound hypercapnia (group 1) and those without rebound hypercapnia (group 2) in their follow-up after the termination of NIMV treatment. Demographic characteristics of the patients, causes of AHRF, duration of NIMV administration, arterial blood gas (ABG) values, APACHE II and SOFA scores, duration of hospitalization (days), need for invasive mechanical ventilation (IMV) and life situations were recorded. Nonparametric Mann-Withney-U test was used for numerical data and Chi-square test for categorical data was used to compare the properties of the groups. Results: 139 patients were included in the study. There was no difference between the demographic characteristics of the groups and the duration of NIMV use, and the length of stay in the ICU and hospital. Thoracic deformity-muscular diseases (8.6% in group 1, 1.2% in group 2), and obesity hypoventilation syndrome (OHS) (17.2% in group 1, 9.9% in group 2) were more in group 1, parenchymal lung diseases was higher in group 2 (6.9% in group 1, 18.5% in group 2). The situation of using oxygen and NIMV devices at home was similar for both groups. While the pH and PaCO2 values of the groups were similar during ICU admission, there was a significant improvement in group 1 compared to group 2 at the first control (p
Type of Medium:
Online Resource
ISSN:
2717-7505
DOI:
10.47582/jompac.813140
Language:
Unknown
Publisher:
Journal of Medicine and Palliative Care
Publication Date:
2020
