In:
Journal of the Association of Physicians of India, Jaypee Brothers Medical Publishing, Vol. 71, No. 04 ( 2023-04-07), p. 73-82
Abstract:
Adverse cardiac remodeling refers to progressive structural and functional modifications in the heart because of increased wall stress in the myocardium, loss of viable myocardium, and neurohormonal stimulation. The guideline-directed medical therapy for Heart failure (HF) includes Angiotensin receptor-neprilysin inhibitor (ARNI) (sacubitril/valsartan), β-blockers, sodium-glucose co-transporter 2 (SGLT2) inhibitors, and mineralocorticoid receptor antagonists (MRA). ARNI is under-prescribed in India despite its attractive safety and efficacy profile. Therefore, the consensus discusses objectives and topics related to ARNI in the management of cardiac remodeling, and experts shared their views on the early timely intervention of effective dosage of ARNI to improve the diagnosis and enhance mortality and morbidity benefits in cardiac reverse remodeling (CRR).
Type of Medium:
Online Resource
ISSN:
0004-5772
DOI:
10.5005/japi-11001-0230
Language:
Unknown
Publisher:
Jaypee Brothers Medical Publishing
Publication Date:
2023
detail.hit.zdb_id:
2139513-5