In:
Archives of Medical Science, Termedia Sp. z.o.o.
Abstract:
This study aimed to investigate whether a rich flaxseed diet could modify the micronuclei frequency, nuclear anomalies and biochemical and anthropometric parameters in metabolic syndrome patients. Material and methods Fifty-eight patients with metabolic syndrome were dichotomized into two groups, namely, the control group (CG) and the intervention group (IG), and the patients in the IG received a diet supplemented with flaxseed. The anthropometric and clinical parameters were measured. Nuclear anomalies isolated from the oral mucosa were analyzed at the beginning and end of the 3-month follow-up. Results After the nutritional follow-up, the percentage of fat was decreased in the CG (before, 45.40%; after, 37.89%, p 〈 0.001). In the IG, the weight (before, 81.03 ±13.17 kg; after, 79.81 ±13.47 kg, p = 0.01), body mass index (before, 32.7 ±5.4; after, 32.2 ±5.6, p = 0.009) and very-low-density lipoprotein (before, 31.96 ±15.23; after, 26.13 ±7.54, p = 0.04) were decreased. The frequencies of MN (micronucleated) and BN (binucleated) cells were decreased in the CG (before, 14.03 ±5.28, after 11.17 ±3.68; before, 2.66 ±3.5, after, 1.10 ±1.66; p = 0.001/0.02, respectively), while in the IG, the frequencies of MN and BN cells and NB (nuclear buds) were decreased (MN before, 4.97 ±5.47, after, 1.38 ±1.97 [p = 0.02]; BN before, 23.69 ±21.93, after, 10.66 ±10.34 [p = 0.007] ; and NB before, 5.10 ±6.63, after, 2.17 ±2.74 [p = 0.03]). Conclusions The group that consumed a diet supplemented with flaxseed showed greater decreases in weight, body mass index and very-low-density lipoprotein than the CG. The numbers of nuclear anomalies were decreased in both groups, but greater mean decreases in micronuclei and binuclear cells were observed in the IG after 3 months.
Type of Medium:
Online Resource
ISSN:
1734-1922
,
1896-9151
DOI:
10.5114/aoms.2020.96978
Language:
Unknown
Publisher:
Termedia Sp. z.o.o.
Publication Date:
2020
detail.hit.zdb_id:
2203781-0
