Format:
Online-Ressource
ISSN:
2196-9736
Content:
Background and study aim: Endoscopic submucosal dissection (ESD) with conventional endoscopes is often difficult for pharyngeal cancers, on account not only of the narrow working space, but also poor maneuverability of the endoscope in the pharynx due to interference by the endotracheal tube and/or hyoid bone. However, we considered that the above problems could possibly be resolved by the use of an ultrathin endoscope for ESD of superficial pharyngeal cancers. The aim of this prospective interventional study was to investigate the feasibility of ESD for superficial pharyngeal cancer using an ultrathin endoscope. Patients and methods: This feasibility study was conducted at NTT Medical Center Tokyo between June 2020 and September 2021, and data of a total of 20 consecutively superficial pharyngeal cancers were analyzed. The primary outcome measure was the R0 resection rate. The ESD completion rate, en-bloc resection rate, procedure time, and frequency of intraoperative and postoperative adverse events were also evaluated as the secondary outcome measures. Results: The data of 16 patients with 20 lesions were included in the analysis. All of the lesions were successfully resected by ultrathin endoscope ESD, and the en-bloc and R0 resection rates were 100% and 85.0% (17/20), respectively; the procedure time was 37.8 ± 28.2 minutes. No intraoperative or postoperative adverse events were encountered in any cases. Conclusions: ESD using an ultrathin endoscope is feasible for superficial pharyngeal cancers and may become established as one of the safe and effective treatment options for these cancers in the future. (Clinical trial registration number:UMIN000040961.)
In:
day:27
In:
month:10
In:
year:2022
In:
Endoscopy International Open, Stuttgart : Thieme, 2013-, (27.10.2022), 2196-9736
Language:
English
URN:
urn:nbn:de:101:1-2022122210070634085270
URL:
https://doi.org/10.1055/a-1968-7501
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2022122210070634085270
URL:
https://d-nb.info/1276358431/34