Umfang:
Online-Ressource
ISSN:
1615-4169
Inhalt:
Abstract: An efficient synthesis of (E)‐5‐aryl (halo) methylenebicyclo[2.2.2]oct‐2‐enes is reported. Lewis acid‐promoted carbohalogenation of 4‐(3‐arylprop‐2‐ynyl)‐cyclohex‐2‐enols in dichloromethane proceeds rapidly to afford the exo‐methylene‐bridged bicycles in good yields. This method also provides an easy access to (E)‐5‐aryl (halo) methylenebicyclo[2.2.1]hept‐2‐enes from the five‐membered ring 2,6‐enynols. The reactions are procedurally simple and high yielding, producing the aryl (halo) methylene‐bridged bicycles in minutes under air and mild conditions.
In:
volume:356
In:
number:18
In:
year:2014
In:
pages:3816-3820
In:
extent:5
In:
Advanced synthesis & catalysis, Weinheim : Wiley-VCH, [2001]-, 356, Heft 18 (2014), 3816-3820 (gesamt 5), 1615-4169
Sprache:
Englisch
DOI:
10.1002/adsc.201400671
URN:
urn:nbn:de:101:1-2023011007041353635094
URL:
https://doi.org/10.1002/adsc.201400671
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023011007041353635094
URL:
https://d-nb.info/1277642249/34
URL:
https://doi.org/10.1002/adsc.201400671
