Format:
Online-Ressource
ISSN:
1521-4109
Content:
Abstract: An interesting phenomenon of the stereoselective interaction between biological macromolecule and amino acid enantiomorphous was described. Firstly, proline enantiomer (L‐ and D‐proline) was assembled on the glassy carbon electrode surface. Then carcinoembryonic antibody (anti‐CEA) was loaded to the enantiomer surface, electrochemical impedance spectroscopy (EIS) was used to monitor the growth of amino acid film. The assembly process was characterized by cyclic voltammetry (CV) and atomic force microscopy (AFM) was applied to image the chiral films. Finally, the developed electrodes had interacted with carcinoembryonic antigen (CEA) in varying concentration solutions. The AFM and amperometric results revealed that the proline enantioner had the chiral recognition function to antibody.
In:
volume:21
In:
number:21
In:
year:2009
In:
pages:2339-2344
In:
extent:6
In:
Electroanalysis, Weinheim : Wiley-VCH-Verl., 1989-, 21, Heft 21 (2009), 2339-2344 (gesamt 6), 1521-4109
Language:
English
DOI:
10.1002/elan.200904688
URN:
urn:nbn:de:101:1-2023041804474115614867
URL:
https://doi.org/10.1002/elan.200904688
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023041804474115614867
URL:
https://d-nb.info/1286483808/34
URL:
https://doi.org/10.1002/elan.200904688