Format:
Online-Ressource
ISSN:
1521-3927
Content:
Abstract: Future advances in designing bioactive materials, such as antithrombotic coatings for cardiovascular stents, will require widely applicable and robust methods of surface modification. In this paper, we report on the development of multifunctional polymer coatings made by chemical vapor deposition (CVD) copolymerization. Polymer coatings of various [2.2]paracyclophane derivatives were co‐deposited in controlled ratios and their chemical composition verified by FT‐IR and X‐ray photoelectron spectroscopy. Furthermore, preliminary biocompatibility of these coatings was assessed using human umbilical vein endothelial cells and 3T3 murine fibroblasts. The parallel immobilization of two different antithrombotic biomolecules onto a CVD‐based copolymer is also demonstrated by orthogonal immobilization strategies.
In:
volume:29
In:
number:11
In:
year:2008
In:
pages:855-870
In:
extent:16
In:
Macromolecular rapid communications, Weinheim : Wiley-VCH, 1980-, 29, Heft 11 (2008), 855-870 (gesamt 16), 1521-3927
Language:
English
DOI:
10.1002/marc.200800101
URN:
urn:nbn:de:101:1-2023072705233864999309
URL:
https://doi.org/10.1002/marc.200800101
URL:
https://nbn-resolving.org/urn:nbn:de:101:1-2023072705233864999309
URL:
https://d-nb.info/1297409981/34
URL:
https://doi.org/10.1002/marc.200800101