Format:
4
ISSN:
2330-1619
Content:
Background: Paroxysmal kinesigenic dyskinesia (PKD) is a rare disorder characterised by brief attacks of chorea, dystonia, or mixed forms precipitated by sudden movement. Methods: Observational study with a cohort of 14 PKD patients and genetic testing for PRRT2 mutations. Results: In a series of 14 PKD patients seen in our clinic at the National Hospital of Neurology, Queen Square, from 2012-2017, we noted tics in 11 patients (79%), which stand in stark contrast to the estimated lifetime prevalence of tics estimated to reach 1%. Conclusions: The two reasons to point out this possible association are the clinical implications and the potential opportunity of a better understanding of shared pathophysiological mechanisms of neuronal hyperexcitability.
Note:
Gesehen am 03.04.2020
In:
Movement disorders clinical practice, New York, NY : Wiley, 2014, 5(2018), 3, Seite 317-320, 2330-1619
In:
volume:5
In:
year:2018
In:
number:3
In:
pages:317-320
In:
extent:4
Language:
English
URL:
https://onlinelibrary.wiley.com/doi/abs/10.1002/mdc3.12615
