Umfang:
1 online resource (372 pages)
ISBN:
9780128200919
Serie:
Issn Ser.
Inhalt:
Front Cover -- Ion Channels and Calcium Signaling in the Microcirculation -- Copyright -- Contents -- Contributors -- Preface -- Acknowledgments -- Chapter One: Introduction to ion channels and calcium signaling in the microcirculation -- 1. What is the microcirculation? -- 2. What are the components of the microcirculation? -- 2.1. Feed arteries and arterioles -- 2.2. Capillaries -- 2.3. Venules -- 2.4. Lymphatics -- 3. Ion channels and Ca signaling in the microcirculation -- 4. Ion channels and the microcirculation: Future directions -- References -- Chapter Two: Ion channels and the regulation of myogenic tone in peripheral arterioles -- 1. Introduction -- 2. Overview of myogenic tone in arterioles and resistance arteries -- 3. Mechanisms of myogenic tone in peripheral arterioles: Role of mechanosensitive G-protein-coupled receptors and inosito ... -- 4. VGCCs and myogenic tone in peripheral arterioles -- 4.1. Non-selective cation channels and myogenic tone in peripheral arterioles -- 4.2. Ca channels and myogenic tone in peripheral arterioles -- 4.3. Lack of a role for PKC in arteriolar myogenic tone in peripheral arterioles -- 4.4. Rho kinase and myogenic tone in peripheral arterioles -- 4.5. Ion channels opposing myogenic tone in peripheral arterioles -- 5. Summary and perspectives -- Acknowledgment -- Disclaimers -- Disclosures -- References -- Chapter Three: Endothelial inwardly-rectifying K channels as a key component of shear stress-induced mechanotransduction -- 1. Introduction -- 2. Arterial hemodynamic environments and general principles of endothelial flow sensation -- 2.1. Role of shear stress in conduit arteries -- 2.2. Role of shear stress in resistance arteries -- 2.3. Principles of flow sensation -- 2.3.1. Adhesion mechanosensitive complex -- 2.3.2. Apical membrane protruding structures.
Anmerkung:
Description based on publisher supplied metadata and other sources
Weitere Ausg.:
9780128200902
Weitere Ausg.:
Erscheint auch als Druck-Ausgabe 9780128200902
Sprache:
Englisch
