Format:
1 online resource (241 pages)
ISBN:
9783319280950
Content:
Intro -- Preface -- Contents -- 1 Introduction -- References -- 2 Cell Cycle as an Object of Control -- 2.1 Cell Cycle and Chemotherapy -- 2.2 Optimization of Cell Cycle Dependent Chemotherapy -- 2.2.1 Compartmental Models of Cell Cycle with Control Action -- 2.2.2 Models with a Single Phase-Specific Killing Agent -- 2.2.3 Multiple Drug Therapy and Control -- 2.2.4 Optimization of Treatment Protocols -- 2.3 Pharmacokinetics and Pharmacodynamics -- 2.4 Resonances, Synchronization, Aftereffects -- 2.5 Drug Resistance in Chemotherapy -- 2.5.1 Simple Models of Drug Resistance -- 2.5.2 Infinite-Dimensional Models of Drug Resistance -- 2.5.3 Model Transformation and Optimization of Therapy -- References -- 3 Therapy Optimization in Population Dynamics Models -- 3.1 Standard Models of Population Dynamics -- 3.2 Tumor Angiogenesis and Antiangiogenic Therapy -- 3.3 Models of Cancer Growth Including Vascularization -- 3.4 Planning Antiangiogenic and Combined Therapies -- 3.5 Models of Gene and Immunotherapy in Cancer Treatment -- References -- 4 Structured Models and Their Use in Modeling Anticancer Therapies -- 4.1 Tumor Growth and Treatment in Two and Three Dimensions -- 4.1.1 Chemotaxis -- 4.1.2 Spheroids and Tumor Cords -- 4.1.3 Multiphase Theory -- 4.1.4 Modeling Desmoplastic Tumor -- 4.1.5 Neovascularization Model -- 4.1.6 Modeling the Tumor Microenvironment Impact -- 4.1.7 Other Models -- 4.2 Models of Angiogenesis -- 4.3 Modeling the Effects of Therapeutic Actions -- 4.4 Structure in Hematopoiesis and Carcinogenesis and Its Role in Cancer Detection, Prevention, and Treatment -- 4.4.1 Stochasticity or Determinism in Stem Cell Systems? -- 4.4.1.1 Deterministic Models of Hematopoiesis -- 4.4.1.2 Leukemic Stem Cells -- 4.4.1.3 Stochastic Models of Hematopoiesis -- 4.4.2 Models of Mutations and Evolution of Disease -- 4.4.2.1 Carcinogenesis Models.
Note:
Description based on publisher supplied metadata and other sources
Additional Edition:
9783319280936
Additional Edition:
Erscheint auch als Druck-Ausgabe 9783319280936
Language:
English
