Format:
37
ISSN:
2050-084X
Content:
Precise organization of growing structures is a fundamental process in developmental biology. In plants, radial growth is mediated by the cambium, a stem cell niche continuously producing wood (xylem) and bast (phloem) in a strictly bidirectional manner. While this process contributes large parts to terrestrial biomass, cambium dynamics eludes direct experimental access due to obstacles in live-cell imaging. Here, we present a cell-based computational model visualizing cambium activity and integrating the function of central cambium regulators. Performing iterative comparisons of plant and model anatomies, we conclude that the receptor-like kinase PXY and its ligand CLE41 are part of a minimal framework sufficient for instructing tissue organization. By integrating tissue-specific cell wall stiffness values, we moreover probe the influence of physical constraints on tissue geometry. Our model highlights the role of intercellular communication within the cambium and shows that a limited number of factors are sufficient to create radial growth by bidirectional tissue production.
Note:
Gesehen am 21.06.2023
In:
eLife, Cambridge : eLife Sciences Publications, 2012, 12(2023) vom: März, Artikel-ID e66627, Seite 1-37, 2050-084X
In:
volume:12
In:
year:2023
In:
month:03
In:
elocationid:e66627
In:
pages:1-37
In:
extent:37
Language:
English
URL:
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