Format:
1 Online-Ressource (112 p)
ISBN:
9781615047338
Series Statement:
Colloquium Series on Integrated Systems Physiology: From Molecule to Function
Content:
Molecular Mechanisms of Body Water Homeostasis -- Colloquium Digital Library of Life Sciences -- Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease -- Abstract -- Key Words -- Contents -- Chapter 1: Water, Water Everywhere -- 1.1 Chapter overview -- 1.2 Body water composition -- 1.2.1 Changes in Water Homeostasis Over the Lifespan -- 1.2.2 Body Water Intake Requirements -- 1.3 Measurement of total body water (TBW) -- 1.3.1 Body Water Compartmentalization -- 1.4 Dehydration -- 1.4.1 Exercise and Water Requirements
Content:
1.5 Environmental modulators of body water composition -- 1.5.1 High Altitude -- 1.5.2 Extremes in Temperature or Humidity -- 1.5.3 Dietary Alterations -- Chapter 2: The Brain, AVP, and Water Balance -- 2.1 Chapter overview -- 2.2 The brain -- 2.3 Vasopressin and related neuropeptides -- 2.3.1 Regulation of Vasopressin Production and Release -- 2.4 Vasopressin receptors -- 2.4.1 Receptor Cloning -- 2.4.2 Receptor Activation and Signaling -- 2.4.3 Receptor Localization -- 2.5 Vasopressin actions -- 2.5.1 Vasopressin and Glomerular Filtration Rate (GFR)
Content:
2.5.2 Vasopressin and Blood Pressure Control -- 2.5.2.1 AVPR2 Are Coupled to Nitric Oxide Generation -- 2.5.2.2 Hypertension May Correlate with Urinary Concentrating Ability -- Chapter 3: Renal Control of Water Reabsorption -- 3.1 Chapter overview -- 3.2 Blood filtration -- 3.3 The countercurrent multiplier mechanism -- 3.3.1 The Na-K-2Cl Cotransporter (NKCC2) -- 3.3.2 Gradient in the Inner Medulla -- 3.4 The collecting duct -- 3.5 Urea transporters -- 3.6 Renal aquaporins -- 3.6.1 Aquaporin-1 -- 3.6.2 Aquaporin-2 -- 3.6.2.1 Short-term AQP2 Regulation -- 3.6.2.2 Long-term AQP2 Regulation
Content:
3.6.2.3 Regulators of AQP2 -- 3.6.3 Aquaporins 3 and 4 -- 3.6.4 Other Aquaporins -- Chapter 4: Hyponatremia -- 4.1 Chapter overview -- 4.2 Causes and forms of hyponatremia -- 4.3 Hyponatremia and the brain -- 4.4 Hyponatremia and bone health -- 4.5 The syndrome of inappropriate antidiuretic hormone (SIADH) -- 4.5.1 Exercise-induced Hyponatremia -- 4.6 Vasopressin Escape and Molecular Mechanisms -- 4.7 Therapies/Interventions -- Chapter 5: Diabetes Insipidus -- 5.1 Chapter overview -- 5.2 Central diabetes insipidus (CDI) -- 5.3 Nephrogenic diabetes insipidus (NDI)
Content:
5.3.1 Mutations in the Vasopressin V2 Receptor -- 5.3.2 Mutations in AQP2 -- 5.4 Acquired NDI -- 5.5 Treatments for DI -- Chapter 6: Additional Pathophysiological States Associated with Impaired Water Balance -- 6.1 Overview -- 6.2 Heart failure -- 6.3 Hypertension -- 6.4 Cirrhosis of the liver -- 6.5 Compulsive water drinking -- 6.6 Burn injuries -- 6.7 Medications that alter fluid dynamics -- 6.7.1 Diuretics -- 6.7.2 Aquaretics -- 6.7.3 Peroxisome Proliferator-Activated Receptor, Subtype γ (PPAR-γ) Agonists -- doi:10.1152/ajprenal.00604.2013 -- References -- Author Biographies
Note:
Description based upon print version of record
Additional Edition:
9781615047321
Additional Edition:
Erscheint auch als Druck-Ausgabe Ecelbarger, Carolyn M Molecular Mechanisms of Body Water Homeostasis San Rafael : Biota Publishing,c2016
Language:
English
Keywords:
Electronic books
URL:
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